Lease expiration date Lease Expiration Date Document Information [Line Items] Operating Expenses [Abstract] Operating expenses Operating Income Loss Income (loss) from operations Entity Emerging Growth Company Entity Emerging Growth Company Income Tax Disclosure [Abstract] Increase Decrease In Prepaid Deferred Expense And Other Assets Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets, Total Number of shares available for future issuance Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Available For Grant Common stock, capital shares reserved for future issuance Payments To Acquire Property Plant And Equipment Additions to property and equipment Payments to Acquire Property, Plant, and Equipment, Total Common stock, $0.001 par value; 300,000,000 shares authorized as of March 31, 2022 and December 31, 2021; 83,257,591 and 83,102,730 shares issued and outstanding as of March 31, 2022 and December 31, 2021, respectively Common Stock Value Common Stock, Value, Issued, Total Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Ending Balance Entity Address State Or Province Entity Address, State or Province Liabilities Total liabilities Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Indefinite Lived Intangible Assets By Major Class [Axis] Indefinite-lived Intangible Assets The number of annual installments in which a share-based payment award vests. Number of installments Share Based Compensation Arrangement By Share Based Payment Award Vesting Number Of Installments General And Administrative Expense [Member] General and Administrative Restricted Cash Restricted cash Restricted Cash, Total Schedule Of Related Party Transactions By Related Party [Table] Schedule Of Related Party Transactions By Related Party [Table] City Area Code City Area Code Lessor, Lease, Description [Line Items] Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents [Abstract] Cash, cash equivalents and restricted cash at the end of period: Commitments And Contingencies Commitments and contingencies (see Note 11) Federal income taxes Federal Income Tax Expense (Benefit), Continuing Operations Federal Income Tax Expense (Benefit), Continuing Operations, Total Basis Of Accounting Policy Policy [Text Block] Basis of Presentation Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Cash, cash equivalents and restricted cash at the end of period Cash, cash equivalents and restricted cash at the beginning of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total Income Statement [Abstract] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Net Cash Provided By Used In Investing Activities Net cash used in investing activities Property and equipment purchases unpaid at period end Capital Expenditures Incurred but Not yet Paid Employee Related Liabilities Current Payroll and payroll related Employee-related Liabilities, Current, Total General And Administrative Expense General and administrative General and Administrative Expense, Total Property Plant And Equipment Net Property and equipment, net Property, Plant and Equipment, Net, Total Property, Plant and Equipment, Net, Beginning Balance Property, Plant and Equipment, Net, Ending Balance Common Stock Shares Issued Common stock, shares issued Common Stock, Shares, Issued, Total Operating lease right-of-use assets, net Operating Lease Right Of Use Asset Right-of-use asset Security Exchange Name Security Exchange Name Range [Member] Statistical Measurement Performance-based Restricted Stock Units Performance Based Restricted Stock Units [Member] Performance based restricted stock units. Additional Office Space Additional Office Space [Member] Additional office space. Cash And Cash Equivalents Fair Value Disclosure Total cash equivalents Fair value assets measured on recurring basis. Fair Value Assets Measured On Recurring Basis [Abstract] Document Period End Date Document Period End Date Restricted cash Restricted Cash, Noncurrent Income Statement Location [Axis] Income Statement Location Office Space Office Space [Member] Office space. Related Party Transaction Expenses From Transactions With Related Party Related party transaction expense Disclosure of accounting policy for unaudited interim financial information. Unaudited Interim Financial Information Policy [Text Block] Unaudited Interim Financial Information Loss Contingencies [Table] Loss Contingencies [Table] Common Stock Shares Authorized Common stock, shares authorized The number of Company directors in control of a related party entity. Related Party Transaction Entity Controlled By Director Number Number of company directors in control of related party entity Use Of Estimates Use of Estimates Operating lease liabilities Current portion of operating lease liabilities Current lease liability Supplemental Cash Flow Information [Abstract] Supplemental disclosure of noncash financing activities Adjustments To Reconcile Net Income Loss To Cash Provided By Used In Operating Activities [Abstract] Adjustments to reconcile net income (loss) to net cash used in operating activities: Antidilutive Securities Excluded From Computation Of Earnings Per Share Amount Number of shares excluded from computation of diluted net income per share Address Type [Domain] State income taxes State and Local Income Tax Expense (Benefit), Continuing Operations State and Local Income Tax Expense (Benefit), Continuing Operations, Total Entity Address, Address Line Two Current Fiscal Year End Date Current Fiscal Year End Date Cash Cash Equivalents Restricted Cash And Restricted Cash Equivalents Period Increase Decrease Including Exchange Rate Effect Net increase (decrease) in cash, cash equivalents and restricted cash Document Information [Table] Operating lease costs Operating Lease, Cost Increase Decrease In Other Operating Assets Other assets Increase (Decrease) in Other Operating Assets, Total Amount of noncash expense related to leasing arrangements. Non-cash lease expense Non Cash Lease Expense Disaggregation Of Revenue [Table] Disaggregation Of Revenue [Table] Counterparty Name [Axis] Counterparty Name Assets [Abstract] Assets 2023 Lessee Operating Lease Liability Payments Due Next Twelve Months Accounts Payable Current Accounts payable Accounts Payable, Current, Total Common Stock Par Or Stated Value Per Share Common stock, par value Weighted Average Number Of Shares Outstanding Basic Basic Weighted average common shares outstanding, basic Weighted Average Number of Shares Outstanding, Basic, Total Shares Outstanding Balance, shares Balance, shares Income Loss From Continuing Operations Before Income Taxes Extraordinary Items Noncontrolling Interest Income (loss) before income taxes Document Type Document Type Preferred stock, $0.001 par value per share; 10,000,000 shares authorized; no shares issued and outstanding as of March 31, 2022, and December 31, 2021 Preferred Stock Value Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Ending Balance Reclassification Reclassification, Comparability Adjustment [Policy Text Block] Operating lease liabilities Noncurrent portion of operating lease liabilities Operating Lease Liability Noncurrent Schedule Of Accrued Liabilities Table [Text Block] Schedule of Accrued Expenses and Other Current Liabilities Assets Current Total current assets Disaggregation Of Revenue [Line Items] Disaggregation Of Revenue [Line Items] Percentage of annual increase in shares that may be issued Percentage of shares of common stock Outstanding Share Based Compensation Arrangement By Share Based Payment Award Annual Increase Percentage The maximum increase in the number of shares that may be issued under a share-based payment arrangement on the first day of each fiscal year, as a percentage of shares outstanding. Stock Options Share-based Payment Arrangement, Option [Member] Business development consulting agreements. Business Development Consulting Agreements [Member] Business Development Consulting Agreements Performance based restricted stock units terms of award Share-based Compensation Arrangement by Share-based Payment Award, Terms of Award Income Tax Expense Benefit Income tax expense Income Tax Expense (Benefit), Total Leases [Abstract] Consolidation Policy [Text Block] Principles of Consolidation Loss Contingencies [Line Items] Loss Contingencies [Line Items] Research and development, including manufacturing and clinical expenditures Accrued Research and Development Expense including Manufacturing and Clinical Expenditures Current Carrying value as of the balance sheet date of obligations incurred and payable for research and development, including, but not limited to, manufacturing and clinical expenses. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Common Stock Shares Outstanding Common stock, shares outstanding Common Stock, Shares, Outstanding, Beginning Balance Common Stock, Shares, Outstanding, Ending Balance Plan Name [Axis] Plan Name Restricted Cash And Cash Equivalents Cash And Cash Equivalents [Member] Cash and Cash Equivalents Operating Expenses Total operating expenses Weighted Average Number Of Shares Outstanding [Abstract] Weighted-average common shares outstanding The aggregate grant date fair value of equity instruments other than options granted during the period. Aggregate grant date fair market value of restricted stock units granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Granted In Period Aggregate Grant Date Fair Value Net Cash Provided By Used In Operating Activities [Abstract] Cash flows from operating activities Lessee Operating Lease Liability Maturity Table [Text Block] Summary of Future Minimum Payments under Operating Leases Earnings Per Share Diluted Diluted Net income (loss) per share, diluted Earnings Per Share, Diluted, Total Earnings Per Share [Abstract] Net income (loss) per share attributable to common stockholders 2024 Lessee, Operating Lease, Liability, to be Paid, Year Two Net Income Loss Net income (loss) Net income (loss) and comprehensive income (loss) Accounts Payable Accrued Liabilities And Other Liabilities Disclosure Current [Text Block] Accrued Expenses and Other Current Liabilities Compensation And Employee Benefit Plans [Text Block] Benefit Plan Research And Development Expense [Member] Research and Development Expense Document Fiscal Period Focus Document Fiscal Period Focus Accounting Policies [Abstract] Entity Address Address Line1 Entity Address, Address Line One Lease commencement date Lease Commencement Date Date which lease or group of leases is set to commence, in YYYY-MM-DD format. Liabilities Current Net liability related to reimbursable costs Total current liabilities Profit Loss Net income (loss) Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Entity Address Postal Zip Code Entity Address, Postal Zip Code Title Of Individual [Axis] Title of Individual Lessee Operating Lease Liability Payments Due Total lease payments Products And Services [Domain] Product and Service Accrued Liabilities And Other Liabilities Accrued expenses and other current liabilities Total accrued expenses and other current liabilities Accrued expenses and other current liabilities Number of additional shares authorized Share Based Compensation Arrangement By Share Based Payment Award Number Of Additional Shares Authorized Increased number of shares available under incentive plan Net Cash Provided By Used In Operating Activities Net cash used in operating activities Location of office space Location of Office Space Location of Office Space Statement Equity Components [Axis] Equity Components Assets Current [Abstract] Current assets Disclosure of accounting policy for significant accounting policies. Significant Accounting Policies Policy [Text Block] Significant Accounting Policies Entity Registrant Name Entity Registrant Name Entity Interactive Data Current Entity Interactive Data Current Entity Address City Or Town Entity Address, City or Town Indefinite Lived Intangible Assets Major Class Name [Domain] Indefinite-lived Intangible Assets, Major Class Name Trading Symbol Trading Symbol Related Party Transactions Disclosure [Text Block] Related Party Transactions Net Cash Provided By Used In Investing Activities [Abstract] Cash flows from investing activities Lessee Operating Lease Liability Undiscounted Excess Amount Less amount representing implied interest Accrued Income Taxes Current Income taxes Local Phone Number Local Phone Number Stockholders Equity Balance Balance Total stockholders’ equity Preferred Stock Shares Issued Preferred stock, shares issued Preferred Stock, Shares Issued, Total Range [Axis] Statistical Measurement Entity Small Business Entity Small Business Disclosure of information about assets at fair value on recurring basis. Fair Value Assets Measured On Recurring Basis [Table] Fair Value Assets Measured On Recurring Basis [Table] Preferred Stock Shares Outstanding Preferred stock, shares outstanding Preferred Stock, Shares Outstanding, Beginning Balance Preferred Stock, Shares Outstanding, Ending Balance Organization Consolidation And Presentation Of Financial Statements [Abstract] Fair Value Measurements Fair Value Hierarchy [Domain] Fair Value Hierarchy and NAV Adjustments To Additional Paid In Capital Sharebased Compensation Requisite Service Period Recognition Value Stock-based compensation expense APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Consulting agreement. Consulting Agreement [Member] Consulting Agreement Common Stock Voting Rights Common stock voting rights per share Defined Contribution Plan Employer Matching Contribution Percent Of Match Defined contribution plan, employer matching contribution, percentage Additional Paid In Capital Additional paid-in capital Additional Paid in Capital, Total Additional Paid in Capital, Beginning Balance Additional Paid in Capital, Ending Balance Fair Value Assets Measured On Recurring Basis [Text Block] Schedule of Financial Assets Measured at Fair Value on Recurring Basis Equity [Abstract] Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Fair Value Assets Measured On Recurring Basis [Line Items] Fair Value Assets Measured On Recurring Basis [Line Items] Related Party Transaction [Line Items] Related Party Transaction [Line Items] Revenue From Contract With Customer [Abstract] Plan Name [Domain] Plan Name Lessee, Lease, Description [Table] Roche license agreement. Roche License Agreement [Member] Roche License Agreement Defined Contribution Plan Cost Recognized Defined contribution plan recognized expense related to matching contributions Retainage Deposit Annual retainer Share Based Compensation Stock-based compensation expense Share-based Payment Arrangement, Noncash Expense, Total Prepaid Expense And Other Assets Current Prepaid expenses and other current assets Long-Lived Tangible Asset [Domain] Related Party Transactions [Abstract] The monetary allowance granted by the landlord to a tenant to entice tenant to move into landlords building which will enable the tenant to prepare the leased premises for tenants occupancy. Lease Hold Improvement Allowance Leasehold improvement allowance Interest And Other Income Interest income and other, net Interest and Other Income, Total Employee Service Share Based Compensation Aggregate Disclosures [Abstract] Net Cash Provided By Used In Financing Activities Net cash provided by financing activities Commitments And Contingencies Disclosure [Abstract] Right of use assets obtained in exchange for operating lease liabilities Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Assets Total assets Fair Value Inputs Level2 [Member] Level 2 Leases Lessee, Operating Leases [Text Block] Stock Issued During Period Shares Stock Options Exercised Issuance of common stock upon exercise of stock options, shares Statement [Line Items] Statement [Line Items] Liabilities And Stockholders Equity Total liabilities and stockholders’ equity Document Quarterly Report Document Quarterly Report Statement Of Cash Flows [Abstract] Additional Paid In Capital [Member] Additional Paid-in Capital Security12b Title Title of 12(b) Security Two thousand twenty incentive award plan. Two Thousand Twenty Incentive Award Plan [Member] 2020 Incentive Award Plan Less amount representing tenant improvement allowance Operating Lease Tenant Improvement Allowance Amount of lessee's undiscounted obligation for lease payments for operating lease for tenant improvement allowance. Fair Value Inputs Level3 [Member] Level 3 Award Type [Domain] Award vesting percentage Share-based Compensation Arrangement by Share-based Payment Award, Award Vesting Rights, Percentage Fair Value By Fair Value Hierarchy Level [Axis] Level 2 Fair Value Inputs Level1 [Member] Level 1 2026 Lessee, Operating Lease, Liability, to be Paid, Year Four Options granted Share Based Compensation Arrangement By Share Based Payment Award Options Grants In Period Gross Nature of business. Nature Of Business [Abstract] Entity Current Reporting Status Entity Current Reporting Status Revenue From Contract With Customer [Text Block] Collaboration Revenue Money Market Funds [Member] Money Market Funds Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Text Block] Schedule of Stock-based Compensation Expense 2022 Lessee Operating Lease Liability Payments Remainder Of Fiscal Year Compensation And Retirement Disclosure [Abstract] Income Statement Location [Domain] Income Statement Location Income taxes payable Accrued Income Taxes, Noncurrent Earnings Per Share Basic Basic Net income (loss) per share, basic Earnings Per Share, Basic, Total Lease expiration month and year Lease Expiration Month And Year Lease Expiration Month And Year Preferred Stock Shares Authorized Preferred stock, shares authorized Minimum Minimum [Member] Cash And Cash Equivalents [Abstract] Cash equivalents Stock Issued During Period Value Stock Options Exercised Issuance of common stock upon exercise of stock options The aggregate amount payable by the Company, as part of a consulting agreement. The payout amount is a success fee calculated as a percentage of certain product sales. Consulting Agreement Success Fee Payout Success fee Number of units granted Share-based Compensation Arrangement by Share-based Payment Award, Equity Instruments Other than Options, Grants in Period Former Address Former Address [Member] Schedule Of Defined Benefit Plans Disclosures [Table] Schedule Of Defined Benefit Plans Disclosures [Table] Net Cash Provided By Used In Financing Activities [Abstract] Cash flows from financing activities Entity Filer Category Entity Filer Category Document Fiscal Year Focus Document Fiscal Year Focus Retained earnings Retained Earnings Accumulated Deficit Retained Earnings (Accumulated Deficit), Total Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Ending Balance Weighted Average Number Diluted Shares Outstanding Adjustment Dilutive effect of outstanding stock options Weighted Average Number Diluted Shares Outstanding Adjustment, Total Income Tax Disclosure [Text Block] Income Taxes Depreciation And Amortization Depreciation and amortization expense Depreciation, Depletion and Amortization, Nonproduction, Total Fair Value Disclosures [Abstract] From 2013 Plan From Two Thousand Thirteen Incentive Plan [Member] From Two Thousand Thirteen Incentive Plan [Member] Maximum [Member] Maximum Maximum Entity Central Index Key Entity Central Index Key 2013 Incentive Plan Two Thousand Thirteen Incentive Plan [Member] Two thousand thirteen incentive plan. Payables And Accruals [Abstract] Entity Tax Identification Number Entity Tax Identification Number Equity Component [Domain] Equity Component Preferred Stock Par Or Stated Value Per Share Preferred stock, par value The entire disclosure for common stock, including, but not limited to, the number of shares issued and outstanding, voting rights, and number of shares reserved for each class of stock. Common Stock [Text Block] Common Stock Number of shares authorized Share Based Compensation Arrangement By Share Based Payment Award Number Of Shares Authorized Statement [Table] Statement [Table] Entity File Number Entity File Number Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Entity Addresses, Address Type [Axis] Retained Earning/ (Accumulated Deficit) Retained Earnings [Member] Revenue From Contract With Customer Excluding Assessed Tax Collaboration revenue Revenue from Contract with Customer, Excluding Assessed Tax, Total Increase Decrease In Accounts Payable Accounts payable Increase (Decrease) in Accounts Payable, Total Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Basis Of Presentation And Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Liabilities Current [Abstract] Current liabilities Disclosure Of Compensation Related Costs Share Based Payments [Text Block] Stock-based Compensation Location of additional office space. Location Of Additional Office Space Location of the additional office space Commitments And Contingencies Disclosure [Text Block] Commitments and Contingencies Total lease liability Operating lease liability Operating Lease Liability Total lease liability Common Stock [Member] Common Stock Director [Member] Director Cover [Abstract] Statement Of Stockholders Equity [Abstract] Amount of lessee's undiscounted obligation for lease payments for operating lease for tenant improvement allowance. Less amount representing future tenant improvement allowance Operating Lease Future Tenant Improvement Allowance Aggregate grant date fair market value The aggregate grant date fair value of options granted during the period. Share Based Compensation Arrangement By Share Based Payment Award Options Granted In Period Aggregate Grant Date Fair Value Disclosure Of Compensation Related Costs Sharebased Payments [Abstract] Restricted Stock Units Restricted Stock Units (RSUs) [Member] Long-Lived Tangible Asset [Axis] Carrying value as of the balance sheet date of obligations incurred and payable for licensing arrangements. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). License fee Accrued License Fees Current Document Transition Report Document Transition Report Proceeds From Stock Options Exercised Proceeds from issuance of common stock for exercise of stock options Research And Development Expense Research and development Research and Development Expense, Total Weighted Average Number Of Diluted Shares Outstanding Diluted Weighted average common shares outstanding, diluted Allocated Share Based Compensation Expense Total stock-based compensation expense The aggregate amount of costs that have been, or will be, reimbursed by the licensee. Costs Reimbursed Amount Costs reimbursed amount Statement Of Financial Position [Abstract] Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received, and fees classified as other. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Professional Fees And Other Current Professional fees and other Stockholders Equity [Abstract] Stockholders’ equity: Nature Of Operations Nature of Business Cash And Cash Equivalents [Axis] Cash and Cash Equivalents Schedule Of Earnings Per Share Basic And Diluted Table [Text Block] Summary of Basic and Diluted Earnings Per Share Increase Decrease In Operating Capital [Abstract] Changes in operating assets and liabilities: 2025 Lessee, Operating Lease, Liability, to be Paid, Year Three Entity Common Stock Shares Outstanding Entity Common Stock, Shares Outstanding Award Type [Axis] Entity Shell Company Entity Shell Company Lessor, Operating Lease, Existence of Option to Extend [true false] Liabilities And Stockholders Equity [Abstract] Liabilities and Stockholders’ Equity Entity Incorporation State Country Code Entity Incorporation, State or Country Code Earnings Per Share [Text Block] Net Income (Loss) Per Share Attributable to Common Stockholders Repurchase Agreement Counterparty Name [Domain] Counterparty Name Amendment Flag Amendment Flag Product Or Service [Axis] Product and Service Increase Decrease In Contract With Customer Liability Deferred revenue Cash And Cash Equivalents At Carrying Value Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value, Total Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Ending Balance New Accounting Pronouncements Policy Policy [Text Block] Recently Adopted Accounting Pronouncements and Recently Issued Accounting Pronouncements Title Of Individual With Relationship To Entity [Domain] Title of Individual Increase Decrease In Accrued Liabilities And Other Operating Liabilities Accrued expenses and other liabilities Defined Benefit Plan Disclosure [Line Items] Defined Benefit Plan Disclosure [Line Items] Summary of Stock-based Compensation Expense by Award Type Share-based Payment Arrangement, Cost by Plan [Table Text Block] Fair Value Disclosures [Text Block] Fair Value Measurements