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HCV external costs Related Party Related Party [Member] Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award Performance based restricted stock units terms of award Tabular disclosure of balance sheet information related to leases. Supplemental Disclosure Of Balance Sheet Information Related To Leases Table [Text Block] Summary of Assets and Liabilities Recorded on Balance Sheet Vesting [Domain] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Options granted Disaggregation Of Revenue [Table] Disaggregation of Revenue [Table] Cumulative increase in percentage of number of shares of common stock issued and outstanding Cumulative Increase in Percentage of Number of Shares of Common Stock Issued and Outstanding Cumulative increase in percentage of number of shares of common stock issued and outstanding. Summary of Basic and Diluted Earnings Per Share Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Investments Classified by Contractual Maturity Date [Table Text Block] Schedule of Fair Value of Available-for-Sale Marketable Securities by Contractual Maturity Net loss per share - basic Net loss per share, basic Earnings Per Share, Basic, Total Earnings Per Share, Basic Number of Shares, Outstanding Number of Shares, Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number Total current liabilities Net liability related to reimbursable costs Liabilities, Current Adjustments to reconcile net loss to net cash used in operating activities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity [Abstract] Janet Hammond Janet Hammond [Member] Janet Hammond. Consolidation Items [Domain] Stockholders’ equity: Equity, Attributable to Parent [Abstract] Shares of common stock [Member] Shares of common stock Entity Small Business Entity Small Business Accumulated deficit Retained Earnings (Accumulated Deficit), Ending Balance Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Total Retained Earnings (Accumulated Deficit) Nature of Operations [Text Block] Nature of Business Issuance of common stock upon vesting of restricted stock units Restricted Stock, Value, Shares Issued Net of Tax Withholdings Stock-based Compensation Share-Based Payment Arrangement [Text Block] Organization, Consolidation and Presentation of Financial Statements [Abstract] Performance based restricted stock units. Performance Based Restricted Stock Units [Member] Performance-based Restricted Stock Units Leases [Abstract] Weighted Average Number Diluted Shares Outstanding Adjustment, Total Dilutive effect of outstanding stock options Weighted Average Number of Shares Outstanding, Diluted, Adjustment Amendment Flag Amendment Flag Product and Service Product and Service [Domain] Loss Contingencies [Line Items] Loss Contingencies [Line Items] Fair Value Assets Measured On Recurring Basis [Abstract] Fair value assets measured on recurring basis. Liabilities and Stockholders’ Equity Liabilities and Equity [Abstract] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Net cash used in operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation Operating lease liabilities Increase (Decrease) in Operating Lease Liability Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description Common Stock Common Stock [Member] Office space. Office Space [Member] Office Space Weighted Average Exercise Price Per Share, Granted Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Unaudited Interim Financial Information Unaudited Interim Financial Information Policy [Text Block] Disclosure of accounting policy for unaudited interim financial information. Merck License Agreement Merck License Agreement [Member] Merck license agreement member. Debt Securities, Available-for-Sale [Line Items] Entity Address, Address Line One Entity Address, Address Line One Level 2 Fair Value Hierarchy and NAV [Axis] Number of company directors in control of related party entity Related Party Transaction Entity Controlled By Director Number The number of Company directors in control of a related party entity. Net loss per share - basic and diluted Earnings Per Share [Abstract] Milestone payments Milestone Payments The amount due upon achievement of specified milestones. Right-of-use asset Operating Lease, Right-of-Use Asset Operating lease right-of-use assets, net Aggregate offering price Stock Issuance Program Authorized Amount The value of shares authorized to be issued under a stock issuance program. Debt Securities, Available-for-Sale, Unrealized Loss Position, Total Debt Securities, Available-for-Sale, Unrealized Loss Position Aggregate fair value Payments to Acquire Debt Securities, Available-for-Sale Purchases of marketable securities Document Type Document Type Entity Central Index Key Entity Central Index Key Debt Securities, Available-for-Sale [Table Text Block] Schedule of Marketable Securities Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Period Increase (Decrease), Including Exchange Rate Effect and Discontinued Operation Net (decrease) increase in cash and cash equivalents Subsequent Event Type [Domain] Number of shares excluded from computation of diluted net income per share Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Common stock, par value Common Stock, Par or Stated Value Per Share Related party transaction expense Operating Costs and Expenses Operating Costs and Expenses, Total Share-Based Payment Arrangement, Tranche One [Member] Tranche One Weighted Average Remaining Contractual Term (years), Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term Debt Securities, Available-for-Sale, Amortized Cost Amortized Cost Amortized Cost Marketable securities Fair Value Marketable Securities Available for Sale Total John Vavricka John Vavricka [Member] John Vavricka. 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Other research and development expenses Document Quarterly Report Document Quarterly Report Entity Address, State or Province Entity Address, State or Province Number of shares, Unvested Number of shares, Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number Number Of Shares,Outstanding Stock units outstanding Preferred Stock, Shares Outstanding, Ending Balance Preferred Stock, Shares Outstanding, Beginning Balance Preferred stock, shares outstanding Preferred Stock, Shares Outstanding Comprehensive loss Comprehensive Income (Loss), Net of Tax, Attributable to Parent Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Unrealized Gains Common stock, capital shares reserved for future issuance Common Stock, Capital Shares Reserved for Future Issuance Schedule of Stock-based Compensation Expense Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Stock Issued During Period, Value, Stock Options Exercised Issuance of common stock upon exercise of stock options Accrued Expenses and Other Current Liabilities Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Interest and Other Income, Total Interest income and other, net Interest and Other Income Collaboration Agreement Collaborative Arrangement Disclosure [Text Block] Equity Option [Member] Stock Options Sales and maturities of marketable securities Proceeds from Sale and Maturity of Marketable Securities Proceeds from sales and maturities of marketable securities Subsequent Event Subsequent Event [Member] Subsequent event Percentage of shares of common stock Outstanding The maximum increase in the number of shares that may be issued under a share-based payment arrangement on the first day of each fiscal year, as a percentage of shares outstanding. Share Based Compensation Arrangement By Share Based Payment Award Annual Increase Percentage Percentage of shares of common stock Outstanding Business Development Consulting Agreements Business Development Consulting Agreements [Member] Business development consulting agreements. Increased number of shares available under plan Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized Number of additional shares authorized Other assets Other Assets, Noncurrent Debt Securities, Available-for-Sale, Current Marketable securities Antidilutive Securities [Axis] Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Award vesting percentage Summary of Significant Accounting Policies Basis of Presentation and Significant Accounting Policies [Text Block] Aggregate Intrinsic Value, Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Summary of Stock-based Compensation Expense by Award Type AOCI Attributable to Parent [Member] Accumulated Other Comprehensive Gain (Loss) Cash and Cash Equivalents Cash and Cash Equivalents [Domain] Carrying value as of the balance sheet date of obligations incurred and payable for research and development, including, but not limited to, manufacturing and clinical expenses. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Research and Development Expense including Manufacturing and Clinical Expenditures Current Research and development, including manufacturing and clinical expenditures Preferred Stock, Value, Issued, Ending Balance Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued Preferred stock, $0.001 par value per share; 10,000,000 shares authorized; no shares issued and outstanding as of March 31, 2026 and December 31, 2025 2015 Employee Stock Purchase Plan Two Thousand and Fifteen Employee Stock Purchase Plan [Member] Two thousand and fifteen employee stock purchase plan. Minimum [Member] Minimum Weighted Average Grant Date Fair Value, Granted Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value Financial Instrument [Axis] Current assets Assets, Current [Abstract] Level 3 Fair Value, Inputs, Level 3 [Member] Segment Reporting [Abstract] Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Granted In Period Aggregate Grant Date Fair Value Aggregate grant date fair market value of restricted stock units granted The aggregate grant date fair value of equity instruments other than options granted during the period. Schedule of Financial Assets Measured at Fair Value on Recurring Basis Fair Value, Assets Measured on Recurring Basis [Table Text Block] Current liabilities Liabilities, Current [Abstract] Nature of business. Nature Of Business [Table] Nature Of Business [Table] Related Party Transactions [Abstract] Balance, shares Balance, shares Shares, Outstanding Accounts Receivable, after Allowance for Credit Loss, Current, Total Accounts Receivable, after Allowance for Credit Loss, Current Accounts receivable Proceeds from Stock Plans Gross proceeds from issuance of common stock Proceeds from issuance of common stock under employee stock purchase plan Commitments and Contingencies Commitments and contingencies (see Note 11) Weighted Average Grant Date Fair Value, Outstanding Weighted Average Grant Date Fair Value, Unvested Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value General and Administrative General and Administrative Expense [Member] General and Administrative Expense Forecast [Member] Forecast Weighted Average Remaining Contractual Term (years), Granted Sharebased Compensation Arrangement by Sharebased Payment Award Options Granted Weighted Average Remaining Contractual Term Sharebased compensation arrangement by sharebased payment award options granted weighted average remaining contractual term. Date which lease or group of leases is set to commence, in YYYY-MM-DD format. Lease Commencement Date Lease commencement date Lessee, Lease, Description [Table] Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Accrued Income Taxes, Current Income taxes Vesting of restricted stock units [Member] Vesting of restricted stock units. Loss Contingencies [Table] Loss Contingencies [Table] Weighted-average number of common shares - basic Weighted Average Number of Shares Outstanding, Basic, Total Weighted average common shares outstanding, basic Weighted Average Number of Shares Outstanding, Basic Scenario [Axis] Shares Acquired Upon Exercise of Stock Options [Member] Shares acquired upon exercise of stock options. Shares Acquired Upon Exercise of Stock Options Document Information [Line Items] Maria Arantxa Horga [Member] Maria Arantxa Horga. Maria Arantxa Horga Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Long-Lived Tangible Asset [Domain] Number of Shares, Granted Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Net of Forfeitures Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Net of Forfeitures, Total Number of shares granted Subsequent Events [Text Block] Subsequent Event Related Party Transactions Related Party Transactions Disclosure [Text Block] APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Stock-based compensation expense APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Location of Office Space Location of Office Space Location of office space Total stockholders’ equity Balance Balance Equity, Attributable to Parent Preferred stock, par value Preferred Stock, Par or Stated Value Per Share Basis of Accounting, Policy [Policy Text Block] Basis of Presentation 2025 Performance-based Restricted Stock Units Two Thousand And Twenty Five Performance-based Restricted Stock Units [Member] Two Thousand And Twenty Five Performance-based Restricted Stock Units Statement of Stockholders' Equity [Abstract] Significant Accounting Policies Significant Accounting Policies Policy [Text Block] Disclosure of accounting policy for significant accounting policies. Share-Based Payment Arrangement, Tranche Two [Member] Tranche Two Use of Estimates, Policy [Policy Text Block] Use of Estimates Defined Benefit Plan Disclosure [Line Items] Defined Benefit Plan Disclosure [Line Items] Entity Address, Address Line Two Fair Value Measurements Fair Value Disclosures [Text Block] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding [Roll Forward] Schedule of Accrued Expenses and Other Current Liabilities Schedule of Accrued Liabilities [Table Text Block] Accrued expenses and other current liabilities Total accrued expenses and other current liabilities Accrued expenses and other current liabilities Accrued Liabilities and Other Liabilities Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration] Segment Reporting, Other Segment Item, Amount Other segment items Plan Name Plan Name [Domain] Increase (Decrease) in Other Operating Assets, Total Other assets Increase (Decrease) in Other Operating Assets Entity [Domain] Weighted Average Exercise Price Per Share, Vested and exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Exercise Price Restricted Stock, Shares Issued Net of Shares for Tax Withholdings Issuance of common stock upon vesting of restricted stock units, shares Related and Nonrelated Parties [Axis] Entity Address, City or Town Entity Address, City or Town Stock Repurchased During Period, Shares Repurchase of common stock, shares Repurchase of common stock, shares Fair Value Assets Measured On Recurring Basis [Table] Fair Value Assets Measured On Recurring Basis [Table] Disclosure of information about assets at fair value on recurring basis. Security Exchange Name Security Exchange Name Counterparty Name Counterparty Name [Axis] Consulting Agreement Consulting Agreement [Member] Consulting agreement. Loss before income taxes Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest FDA Acceptance [Member] FDA acceptance. FDA Acceptance Number of Shares, Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number Amount of deferred tax asset used to offset taxable income during the period. Deferred tax assets to offset taxable income Deferred Tax Assets To Offset Taxable Income Antidilutive Securities, Name [Domain] Total cash, cash equivalents and restricted cash Cash, Cash Equivalent, Restricted Cash, and Restricted Cash Equivalent, Continuing Operation Cash and cash equivalents at the beginning of period Cash and cash equivalents at the end of period Total cash and cash equivalents Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Statistical Measurement Statistical Measurement [Domain] Total current assets Assets, Current Total stock-based compensation expense Compensation expense Stock based compensation Document Period End Date Document Period End Date Title of Individual Title and Position [Axis] Employee Stock Purchase Plan Employee Stock Purchase Plan [Member] Employee stock purchase plan. Fair Value Hierarchy and NAV Fair Value Hierarchy and NAV [Domain] Defined contribution plan recognized expense related to matching contributions Defined Contribution Plan, Cost Statement of Financial Position [Abstract] Restricted Stock Units (RSUs) [Member] Restricted Stock Units Arantxa Horga [Member] Arantxa Horga. Arantxa Horga Antidilutive Security, Excluded EPS Calculation [Table] Vesting [Axis] Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Other comprehensive loss Fair Value Assets Measured On Recurring Basis [Line Items] Fair Value Assets Measured On Recurring Basis [Line Items] Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Other General And Administrative [Member] Other general and administrative. Other general and administrative Number of held securities Debt Securities, Available-for-Sale, Unrealized Loss Position, Number of Positions Benefit Plan Compensation and Employee Benefit Plans [Text Block] Provision for income taxes Current Income Tax Expense (Benefit) Current Income Tax Expense (Benefit), Total Two thousand and twenty four performance-based restricted stock units. Two Thousand And Twenty Four Performance-based Restricted Stock Units [Member] 2024 Performance-based Restricted Stock Units Roche License Agreement Roche License Agreement [Member] Roche license agreement. Financial Instruments [Domain] Vesting service period Share-Based Compensation Arrangement by Share-Based Payment Award, Award Requisite Service Period Indefinite-lived Intangible Assets, Major Class Name Indefinite-Lived Intangible Assets, Major Class Name [Domain] Weighted-average number of common shares - diluted Weighted average common shares outstanding, diluted Weighted Average Number of Shares Outstanding, Diluted Weighted average common shares outstanding, diluted Entity File Number Securities Act File Number Stock-based compensation expense, shares Adjustments To Additional Paid In Capital Share based Compensation Requisite Service Period Recognition Shares Adjustments to additional paid in capital share based compensation requisite service period recognition shares. OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Unrealized loss on available-for-sale investments Cover [Abstract] Early Stage Discovery External Costs [Member] Early stage discovery external costs. Early stage discovery external costs Prepaid expenses and other current assets Prepaid Expense and Other Assets, Current Number of shares, Cancelled Number of units cancelled due to terminations Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Scenario [Domain] US Treasury obligations US Treasury Securities [Member] U.S. Treasury obligations Number of shares available for grant Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Number of shares authorized Number of Operating Segments Number of operating segments Sale of Stock [Domain] Segment Information Segment Reporting Disclosure [Text Block] General and administrative General and Administrative Expense Total general and administrative Total general and administrative Jeffries Jefferies LLC [Member] Jefferies LLC. Number of Shares, Cancelled Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures and Expirations in Period, Total Weighted Average Exercise Price Per Share, Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price Weighted Average Remaining Contractual Term and Aggregate Intrinsic Value Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Additional Disclosures [Abstract] New Accounting Pronouncements, Policy [Policy Text Block] Recently Issued Accounting Pronouncements Summary of Future Minimum Payments under Operating Leases Lessee, Operating Lease, Liability, to be Paid, Maturity [Table Text Block] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Triggering Expense Recognition Percentage Triggering expense recognition The amount of expense recognized as of the balance sheet date due to metric achievement probability, as a percentage. Vesting contractual term Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period Former Address [Member] Former Address Unrecognized compensation expense Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount COVID-19 external costs COVID Nineteen External Costs [Member] COVID nineteen external costs. 2020 Incentive Award Plan Two Thousand Twenty Incentive Award Plan [Member] Two thousand twenty incentive award plan. Common Stock, Shares, Outstanding, Ending Balance Common Stock, Shares, Outstanding, Beginning Balance Common stock, shares outstanding Common Stock, Shares, Outstanding Current lease liability Current portion of operating lease liabilities Operating lease liabilities Document Transition Report Document Transition Report Share-Based Payment Arrangement, Additional Disclosure [Abstract] Total operating expenses Operating Expenses Research and development Research and Development Expense Total research and development expense Total research and development expense Lessee, Operating Leases [Text Block] Leases Payments for Repurchase of Common Stock Repurchase of common stock Statement of Cash Flows [Abstract] The number of equity-based payment instruments, excluding stock (or unit) options, that were released during the reporting period. Number of shares, Released Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Released In Period Number of shares, Released Summary of Stock Options Activity Share-Based Payment Arrangement, Option, Activity [Table Text Block] Dengue External Costs [Member] Dengue external costs. Dengue external costs Net Loss Per Share Earnings Per Share [Text Block] Summary of Restricted Stock Units Share-Based Payment Arrangement, Restricted Stock Unit, Activity [Table Text Block] Net loss Net loss Net loss Aggregate Intrinsic Value, Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value Operating Lease, Cost Operating lease costs Nature Of Business [Abstract] Nature of business. Aggregate Intrinsic Value, Vested and exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Aggregate Intrinsic Value Assets Assets [Abstract] Increase (Decrease) in Prepaid Expense and Other Assets, Total Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets Document Fiscal Year Focus Document Fiscal Year Focus Cash flows from investing activities Cash Provided by (Used in) Investing Activity, Including Discontinued Operation [Abstract] Retirement Benefits [Abstract] Accounts Payable, Current, Total Accounts payable Accounts Payable, Current Research and Development Expense Research and Development Expense [Member] Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Marketable Securities Defined contribution plan, employer matching contribution, percentage Defined Contribution Plan, Employer Matching Contribution, Percent of Match Two thousand and twenty two performance based restricted stock units. Two Thousand And Twenty Two Performance Based Restricted Stock Units [Member] 2022 Performance-based Restricted Stock Units Proceeds from Stock Options Exercised Proceeds from issuance of common stock upon exercise of stock options Fair Value Disclosures [Abstract] Commitments and Contingencies Disclosure [Abstract] Vested Stock Options [Member] Vested stock options. Vested Stock Options Share-Based Payment Arrangement [Abstract] Debt Securities, Available-for-Sale [Abstract] Assets, Fair Value Disclosure Total Assets measured at fair value Sale of Stock [Axis] The aggregate grant date fair value of options granted during the period. Aggregate average grant date fair value per option granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Options Granted In Period Aggregate Grant Date Fair Value Success fee Consulting Agreement Success Fee Payout The aggregate amount payable by the Company, as part of a consulting agreement. The payout amount is a success fee calculated as a percentage of certain product sales. Cash Provided by (Used in) Investing Activity, Including Discontinued Operation Net cash provided by investing activities Number of Patients Enrolled for the HCV Number of Patients Enrolled for the HCV Number of patients enrolled for the HCV. Title of 12(b) Security Title of 12(b) Security Schedule of Segment Reporting Information, by Segment [Table] Weighted Average Grant Date Fair Value, Cancelled Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Money Market Funds Money Market Funds [Member] Related and Nonrelated Parties [Domain] Income Taxes Income Tax Disclosure [Text Block] Document Information [Table] Legal Entity [Axis] Changes in operating assets and liabilities: Adjustment to Reconcile Net Income to Cash Provided by (Used in) Operating Activity, Increase (Decrease) in Operating Capital [Abstract] Weighted Average Exercise Price Per Share, Outstanding Weighted Average Exercise Price Per Share, Outstanding Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Income Tax Disclosure [Abstract] Additional Paid-in Capital Additional Paid-in Capital [Member] Accrued expenses and other liabilities Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Shares Not Acquired Upon Exercise of Stock Options [Member] Shares not acquired upon exercise of stock options. Shares Not Acquired Upon Exercise of Stock Options Share Repurchase Program, Authorized, Amount Maximum amount authorized repurchase common stock Income Statement Location Statement of Income Location, Balance [Axis] Trading Symbol Trading Symbol Related Party Transaction [Table] Schedule Of Related Party Transactions By Related Party [Table] Sales Agreement Open Market Sale Agreement [Member] Open market sale agreement. Director Director [Member] HEV External Costs [Member] HEV external costs HEV external costs Subsequent Event Type [Axis] Employee-related Liabilities, Current, Total Payroll and payroll related Employee-related Liabilities, Current Cash flows from financing activities Cash Provided by (Used in) Financing Activity, Including Discontinued Operation [Abstract] Total lease payments Lessee, Operating Lease, Liability, to be Paid Total lease payments From Two Thousand Thirteen Incentive Plan [Member] From Two Thousand Thirteen Incentive Plan [Member] From 2013 Plan Equity Components Equity Components [Axis] 2020 Employee Stock Purchase Plan Two Thousand and Twenty Employee Stock Purchase Plan [Member] Two thousand and twenty employee stock purchase plan. Weighted Average Remaining Contractual Term (years), Vested and exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Weighted Average Remaining Contractual Term Research and Development Credit Adjustment The aggregate credit recorded during the period to research and development expense as a result of adjustments to amounts originally reported and the close out of certain activities. Research and development net credits adjustment Two thousand thirteen incentive plan. Two Thousand Thirteen Incentive Plan [Member] 2013 Incentive Plan Equity Component Equity Component [Domain] Lessor, Lease, Description [Line Items] Address Type [Domain] Entity Controlled by Director Entity Controlled by Director [Member] Entity controlled by director. Issuance of common stock under ESPP, shares Issuance of common stock under employee stock purchase plan, shares Stock Issued During Period, Shares, Employee Stock Purchase Plans Award contractual term Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period Depreciation, Depletion and Amortization, Nonproduction, Total Depreciation and amortization expense Depreciation, Depletion and Amortization, Nonproduction Common stock voting rights per share Common Stock, Voting Rights Maximum Maximum Maximum [Member] Entity Addresses, Address Type [Axis] Statistical Measurement Statistical Measurement [Axis] Weighted Average Exercise Price Per Share, Exercised Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price Common Stock, Value, Issued, Ending Balance Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Total Common Stock, Value, Issued Common stock, $0.001 par value; 300,000,000 shares authorized; 80,027,099 and 78,126,796 shares issued and outstanding as of March 31, 2026 and December 31, 2025, respectively Common Stock [Text Block] The entire disclosure for common stock, including, but not limited to, the number of shares issued and outstanding, voting rights, and number of shares reserved for each class of stock. Common Stock Cash equivalents Cash and Cash Equivalents [Abstract] Principles of Consolidation Consolidation, Policy [Policy Text Block] Preferred stock, shares authorized Preferred Stock, Shares Authorized Payment, Tax Withholding, Share-Based Payment Arrangement Issuance of restricted stock units Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss, Total Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Debt securities in unrealized loss position Related Party Transaction [Line Items] Related Party Transaction [Line Items] Employee Stock [Member] Employee Stock Purchase Plan Employee Stock Purchase Plan Collaboration Agreement Revenue from Contract with Customer [Text Block] Debt Securities, Available-for-Sale, Allowance for Credit Loss, Not Previously Recorded Marketable debt securities, charges for credit-related impairments Entity Registrant Name Entity Registrant Name Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Unrealized Losses Additional Paid in Capital, Ending Balance Additional Paid in Capital, Beginning Balance Additional Paid in Capital, Total Additional paid-in capital Additional Paid in Capital Lessor, Operating Lease, Existence of Option to Extend [true false] Subsequent Events [Abstract] Income tax expense (benefit) Income Tax Expense (Benefit), Total Income Tax Expense (Benefit) Income tax expense Commission percentage of aggregate gross proceeds from each sale of shares Commission Rate The commission rate the Company agreed to pay for shares sold under a Sales Agreement, as a percentage of aggregate gross sales proceeds from each sale of shares. Stock Repurchased During Period, Value Repurchase of common stock Aggregate price Repurchase of common stock Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Compensation And Related Expenses [Member] Compensation and related expenses. Compensation and related expenses Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated other comprehensive (loss) gain Consolidation Items [Axis] Federal Income Tax Expense (Benefit), Continuing Operations, Total Federal Income Tax Expense (Benefit), Continuing Operations Federal income taxes Number of units granted Number of shares, Granted Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Share Based Compensation Arrangement By Share Based Payment Award Options Granted In Period Aggregate Grant Date Fair Value The aggregate grant date fair value of options granted during the period. Aggregate grant date fair market value Total assets Assets Income Statement [Abstract] Potential milestone amount Potential Milestone Amount The amount due upon achievement of specified milestones. Accrued License Fees Current License fee Carrying value as of the balance sheet date of obligations incurred and payable for licensing arrangements. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Net loss per share - diluted Net loss per share, diluted Earnings Per Share, Diluted, Total Earnings Per Share, Diluted Schedule of Segment Reporting Information, by Segment [Table Text Block] Schedule of Segment Expenses and Segment Operating Loss Operating Segment Operating Segments [Member] Title of Individual Title and Position [Domain] City Area Code City Area Code Other Comprehensive Income (Loss), Net of Tax, Total Other Comprehensive Income (Loss), Net of Tax Other comprehensive income (loss) Other comprehensive loss Schedule Of Defined Benefit Plans Disclosures [Table] Defined Benefit Plan [Table] Counterparty Name Counterparty Name [Domain] Gross proceeds from issuance of common stock Issuance of common stock under employee stock purchase plan Stock Issued During Period, Value, Employee Stock Purchase Plan Segment Reporting Information [Line Items] Stock Issued During Period, Shares, Restricted Stock Award, Gross Issuance of common stock upon vesting of restricted stock units, shares Lease Expiration Date Lease expiration date Professional fees and other Accrued Professional Fees And Other Current Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received, and fees classified as other. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Property, Plant and Equipment, Net, Ending Balance Property, Plant and Equipment, Net, Beginning Balance Property, Plant and Equipment, Net, Total Property and equipment, net Property, Plant and Equipment, Net Number of Shares, Vested and exercisable Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Exercisable, Number Corporate Bond Securities [Member] Corporate bonds Loss from operations Operating Income (Loss) Accumulated Deficit Retained Earnings [Member] Cash and Cash Equivalents Cash and Cash Equivalents [Axis] Share-based Payment Arrangement, Noncash Expense, Total Stock-based compensation expense Share-Based Payment Arrangement, Noncash Expense Level 1 Fair Value, Inputs, Level 1 [Member] Cash Provided by (Used in) Financing Activity, Including Discontinued Operation Net cash provided by (used in) financing activities Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block] Summary of Antidilutive Securities Excluded from Computation of Net Loss Per Share Debt Securities, Available-for-Sale [Table] Entity Interactive Data Current Entity Interactive Data Current Income Statement Location Statement of Income Location, Balance [Domain] Two Thousand And Twenty Six Performance-based Restricted Stock Units [Member] Two Thousand And Twenty Six Performance-based Restricted Stock Units. 2026 Performance-based Restricted Stock Units Amount Of Potential Milestone Payable Upon Accepance Of New Drug Application Amount of potential milestone payable upon accepance of new drug application. Amount of potential milestone payable upon accepance of new drug application Cash flows from operating activities Cash Provided by (Used in) Operating Activity, Including Discontinued Operation [Abstract] Accretion (Amortization) of Discounts and Premiums, Investments Accretion of premium and discounts on marketable securities Issuance of common stock upon vesting of restricted stock units Issuance Of Common Stock Upon Vesting Of Restricted Stock Units Value Issuance of common stock upon vesting of restricted stock units value. Entity Tax Identification Number Entity Tax Identification Number Local Phone Number Local Phone Number Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Rolling after One Through Five Years, Fair Value Maturing after one year through five years Unrecognized compensation expense Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount Weighted Average Number of Shares Outstanding, Diluted [Abstract] Weighted-average number of common shares - basic and diluted Debt Securities, Available-for-Sale, Maturity, Allocated and Single Maturity Date, Rolling within One Year, Fair Value Maturing in one year or less Milestone Expense The amount of milestone expense recognized during the period. Milestone expense Accounting Policies [Abstract] Disaggregation Of Revenue [Line Items] Disaggregation of Revenue [Line Items] Commercial Paper [Member] Commercial paper Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Number of shares available for future issuance Common stock available for issuance Remaining weighted average period for recognize compensation expense Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition Cash, Cash Equivalents, and Short-Term Investments, Total Cash and cash equivalents and marketable securities Cash and cash equivalents and marketable securities Jean-Pierre Sommadossi [Member] Jean-Pierre Sommadossi. Jean-Pierre Sommadossi Entity Emerging Growth Company Entity Emerging Growth Company Weighted Average Remaining Contractual Term (years), Vested and expected to vest Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term Indefinite-lived Intangible Assets Indefinite-Lived Intangible Assets [Axis] Consulting and professional fees Consulting And Professional Fees [Member] Consulting and professional fees.