Entity Address, City or Town Entity Address, City or Town Fair Value Disclosures [Abstract] Earnings Per Share [Abstract] Net income (loss) per share attributable to common stockholders Fair Value, Inputs, Level 1 [Member] Level 1 Schedule of Accrued Liabilities [Table Text Block] Schedule of Accrued Expenses and Other Current Liabilities Net Cash Provided by (Used in) Financing Activities [Abstract] Cash flows from financing activities Nature of Business [Line Items] Nature Of Business [Line Items] Nature of business. Amendment Flag Amendment Flag Number of shares authorized Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Authorized Operating lease right-of-use assets, net Operating Lease, Right-of-Use Asset Right-of-use asset Document Quarterly Report Document Quarterly Report Proceeds from maturities of debt securities Proceeds from Sale of Debt Securities, Available-for-Sale Lessee, Operating Lease, Liability, Undiscounted Excess Amount Less amount representing implied interest Cash and Cash Equivalents [Domain] Cash and Cash Equivalents Statement [Table] Statement [Table] Operating lease liabilities Noncurrent portion of operating lease liabilities Operating Lease, Liability, Noncurrent The number of annual installments in which a share-based payment award vests. Number of installments Share Based Compensation Arrangement By Share Based Payment Award Vesting Number Of Installments Issuance of common stock under ESPP, shares Issuance of common stock Stock Issued During Period, Shares, Employee Stock Purchase Plans Preferred Stock, Shares Outstanding Preferred stock, shares outstanding Preferred Stock, Shares Outstanding, Beginning Balance Preferred Stock, Shares Outstanding, Ending Balance Common Stock, Capital Shares Reserved for Future Issuance Common stock, capital shares reserved for future issuance Nature of Operations [Text Block] Nature of Business Entity Addresses, Address Type [Axis] Product and Service [Axis] Product and Service Employee-related Liabilities, Current Payroll and payroll related Employee-related Liabilities, Current, Total Leases Lessee, Operating Leases [Text Block] Stock Options Share-Based Payment Arrangement, Option [Member] Liabilities and Equity Total liabilities and stockholders’ equity Other Comprehensive Loss AOCI Including Portion Attributable to Noncontrolling Interest [Member] Plan Name [Domain] Plan Name Reclassification Reclassification, Comparability Adjustment [Policy Text Block] Weighted Average Number of Shares Outstanding, Diluted [Abstract] Weighted-average common shares outstanding Entity Incorporation, State or Country Code Entity Incorporation, State or Country Code Income Statement [Abstract] Proceeds from issuance of common stock under ESPP Gross proceeds from issuance of common stock Proceeds from Stock Plans Debt Securities, Available-for-Sale [Abstract] Sale of Stock [Domain] Liabilities, Current Net liability related to reimbursable costs Total current liabilities Cumulative increase in percentage of number of shares of common stock issued and outstanding. Cumulative Increase in Percentage of Number of Shares of Common Stock Issued and Outstanding Cumulative increase in percentage of number of shares of common stock issued and outstanding Issuance of common stock under ESPP Gross proceeds from issuance of common stock Stock Issued During Period, Value, Employee Stock Purchase Plan 2025 Lessee, Operating Lease, Liability, to be Paid, Year Three Increase (Decrease) in Contract with Customer, Liability Deferred revenue Preferred Stock, Shares Authorized Preferred stock, shares authorized Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table] Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table] State income taxes State and Local Income Tax Expense (Benefit), Continuing Operations State and Local Income Tax Expense (Benefit), Continuing Operations, Total Entity Small Business Entity Small Business Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents Cash, cash equivalents and restricted cash at the end of period Cash, cash equivalents and restricted cash at the beginning of period Cash, Cash Equivalents, Restricted Cash and Restricted Cash Equivalents, Total Assets, Current Total current assets Indefinite-Lived Intangible Assets [Axis] Indefinite-lived Intangible Assets 2022 Lessee, Operating Lease, Liability, to be Paid, Remainder of Fiscal Year Weighted Average Number of Shares Outstanding, Basic Basic Weighted average common shares outstanding, basic Weighted Average Number of Shares Outstanding, Basic, Total Performance-based Restricted Stock Units Performance Based Restricted Stock Units [Member] Performance based restricted stock units. Prior office space. Prior Office Space [Member] Prior Office Space City Area Code City Area Code Additional Office Space Additional Office Space [Member] Additional office space. Options cancelled Fair value assets measured on recurring basis. Fair Value Assets Measured On Recurring Basis [Abstract] Share-Based Payment Arrangement [Abstract] Liabilities Total liabilities Document Period End Date Document Period End Date Asset-backed securities Asset-Backed Securities [Member] Office Space Office Space [Member] Office space. Disclosure of accounting policy for unaudited interim financial information. Unaudited Interim Financial Information Policy [Text Block] Unaudited Interim Financial Information Amortized Cost Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost The number of Company directors in control of a related party entity. Related Party Transaction Entity Controlled By Director Number Number of company directors in control of related party entity Statistical Measurement [Axis] Statistical Measurement Amount of shares authorized to be issued under a stock issuance program. Stock Issuance Program Authorized Amount Aggregate offering price Assets Total assets Earnings Per Share, Diluted Diluted Net income (loss) per share, diluted Earnings Per Share, Diluted, Total Share-Based Payment Arrangement, Additional Disclosure [Abstract] Entity Address, Postal Zip Code Entity Address, Postal Zip Code Document Fiscal Period Focus Document Fiscal Period Focus Restricted Cash Restricted cash Restricted Cash, Total Current Income Tax Expense (Benefit), Total Current Income Tax Expense (Benefit) Provision for income taxes Increase (Decrease) in Accounts Receivable Accounts receivable Preferred stock, $0.001 par value per share; 10,000,000 shares authorized; no shares issued and outstanding as of September 30, 2022, and December 31, 2021 Preferred Stock, Value, Issued Preferred Stock, Value, Issued, Total Preferred Stock, Value, Issued, Beginning Balance Preferred Stock, Value, Issued, Ending Balance APIC, Share-Based Payment Arrangement, Increase for Cost Recognition Stock-based compensation expense APIC, Share-based Payment Arrangement, Increase for Cost Recognition, Total Lessor, Operating Lease, Existence of Option to Extend [true false] Counterparty Name [Domain] Counterparty Name Total lease liability Operating lease liability Operating Lease, Liability Total lease liability Net Cash Provided by (Used in) Financing Activities Net cash provided by financing activities Statement of Financial Position [Abstract] Entity File Number Entity File Number Statement of Cash Flows [Abstract] Statistical Measurement [Domain] Statistical Measurement Statement of Stockholders' Equity [Abstract] Sale of Stock [Axis] Accretion of premium and discounts on marketable securities Amortization of Debt Discount (Premium) Concentration of Credit Risk and Off-balance Sheet Risk Concentration of Credit Risk and Off Balance Sheet Risk [Policy Text Block] Concentration of credit risk and off balance sheet risk. Legal Entity [Axis] Fair Value Disclosures [Text Block] Fair Value Measurements Retainage Deposit Annual retainer Other comprehensive income (loss) Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent [Abstract] Proceeds from Stock Options Exercised Proceeds from issuance of common stock for exercise of stock options Percentage of annual increase in shares that may be issued Percentage of shares of common stock Outstanding Share Based Compensation Arrangement By Share Based Payment Award Annual Increase Percentage The maximum increase in the number of shares that may be issued under a share-based payment arrangement on the first day of each fiscal year, as a percentage of shares outstanding. Business development consulting agreements. Business Development Consulting Agreements [Member] Business Development Consulting Agreements Weighted Average Number of Shares Outstanding, Diluted, Adjustment Dilutive effect of outstanding stock options Weighted Average Number Diluted Shares Outstanding Adjustment, Total Revenue from Contract with Customer [Text Block] Collaboration Revenue Concentration of Credit Risk and Off-balance Sheet Risk Concentration Risk, Credit Risk, Policy [Policy Text Block] Antidilutive Securities [Axis] Related Party Transaction, Expenses from Transactions with Related Party Related party transaction expense Preferred Stock, Par or Stated Value Per Share Preferred stock, par value Unrealized Gain Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax Cash and cash equivalents and marketable securities Cash, Cash Equivalents, and Short-Term Investments, Total Research and development, including manufacturing and clinical expenditures Accrued Research and Development Expense including Manufacturing and Clinical Expenditures Current Carrying value as of the balance sheet date of obligations incurred and payable for research and development, including, but not limited to, manufacturing and clinical expenses. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Weighted Average Number of Shares Outstanding, Diluted Diluted Weighted average common shares outstanding, diluted Two thousand and fifteen employee stock purchase plan. Two Thousand and Fifteen Employee Stock Purchase Plan [Member] 2015 Employee Stock Purchase Plan General and Administrative Expense [Member] General and Administrative Commercial paper Commercial Paper [Member] Current Fiscal Year End Date Current Fiscal Year End Date Financial Instruments [Domain] The aggregate grant date fair value of equity instruments other than options granted during the period. Aggregate grant date fair market value of restricted stock units granted Share Based Compensation Arrangement By Share Based Payment Award Equity Instruments Other Than Options Granted In Period Aggregate Grant Date Fair Value Nature Of Business [Table] Nature Of Business [Table] Nature of business. Entity Address, Address Line One Entity Address, Address Line One Supplemental Cash Flow Information [Abstract] Supplemental disclosure of noncash financing activities Lease expiration date Lease Expiration Date Marketable Securities Investments in Debt and Marketable Equity Securities (and Certain Trading Assets) Disclosure [Text Block] Restricted cash Restricted Cash, Noncurrent Income tax benefit (expense) Income Tax Expense (Benefit) Income Tax Expense (Benefit), Total Increase (Decrease) in Operating Lease Liability Operating lease liabilities Income Tax Disclosure [Text Block] Income Taxes Preferred Stock, Shares Issued Preferred stock, shares issued Preferred Stock, Shares Issued, Total Lease commencement date Lease Commencement Date Date which lease or group of leases is set to commence, in YYYY-MM-DD format. Payments to Acquire Property, Plant, and Equipment Additions to property and equipment Payments to Acquire Property, Plant, and Equipment, Total Income Tax Disclosure [Abstract] Address Type [Domain] Fair Value Hierarchy and NAV [Axis] Level 2 Equity [Abstract] Operating Income (Loss) Income (loss) from operations Location of office space Location of Office Space Location of Office Space Performance based restricted stock units terms of award Share-Based Compensation Arrangement by Share-Based Payment Award, Terms of Award Disclosure of accounting policy for significant accounting policies. Significant Accounting Policies Policy [Text Block] Significant Accounting Policies Accrued Liabilities and Other Liabilities Accrued expenses and other current liabilities Total accrued expenses and other current liabilities Accrued expenses and other current liabilities Aggregate fair value Debt Securities, Available-for-Sale, Unrealized Loss Position Debt Securities, Available-for-Sale, Unrealized Loss Position, Total Common Stock, Voting Rights Common stock voting rights per share Entity Filer Category Entity Filer Category Operating Expenses Total operating expenses Entity Current Reporting Status Entity Current Reporting Status Marketable securities Debt Securities, Available-for-Sale, Current Stockholders' Equity Attributable to Parent Balance Balance Total stockholders’ equity Debt securities in unrealized loss position Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss, Total Entity Tax Identification Number Entity Tax Identification Number Income Statement Location [Axis] Income Statement Location Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Number of units cancelled due to terminations Common stock, $0.001 par value; 300,000,000 shares authorized as of September 30, 2022 and December 31, 2021; 83,287,639 and 83,102,730 shares issued and outstanding as of September 30, 2022 and December 31, 2021, respectively Common Stock, Value, Issued Common Stock, Value, Issued, Total Common Stock, Value, Issued, Beginning Balance Common Stock, Value, Issued, Ending Balance Retained Earnings (Accumulated Deficit) Retained Earnings (Accumulated Deficit), Total Retained Earnings (Accumulated Deficit), Beginning Balance Retained Earnings (Accumulated Deficit), Ending Balance Retained earnings (accumulated deficit) Equity Components [Axis] Equity Components Cash and Cash Equivalents Cash and Cash Equivalents, Policy [Policy Text Block] Leases [Abstract] Disaggregation of Revenue [Table] Disaggregation Of Revenue [Table] Entity Emerging Growth Company Entity Emerging Growth Company Disclosure of information about assets at fair value on recurring basis. Fair Value Assets Measured On Recurring Basis [Table] Fair Value Assets Measured On Recurring Basis [Table] Operating Expenses [Abstract] Operating expenses Consulting agreement. Consulting Agreement [Member] Consulting Agreement Deferred Tax Assets To Offset Taxable Income Deferred tax assets to offset taxable income Amount of deferred tax asset used to offset taxable income during the period. Debt Securities, Available-for-Sale [Table] Retirement Benefits [Abstract] Depreciation, Depletion and Amortization, Nonproduction Depreciation and amortization expense Depreciation, Depletion and Amortization, Nonproduction, Total Document Transition Report Document Transition Report Assets measured at fair value Total Assets, Fair Value Disclosure Employee stock purchase plan. Employee Stock Purchase Plan [Member] Employee Stock Purchase Plan Accounts Payable, Accrued Liabilities, and Other Liabilities Disclosure, Current [Text Block] Accrued Expenses and Other Current Liabilities Commitments and Contingencies Disclosure [Text Block] Commitments and Contingencies Accumulated other comprehensive loss Accumulated Other Comprehensive Income (Loss), Net of Tax Accumulated Other Comprehensive Income (Loss), Net of Tax, Total Accounts receivable Accounts Receivable, after Allowance for Credit Loss, Current Accounts Receivable, after Allowance for Credit Loss, Current, Total Marketable Securities Entity Common Stock, Shares Outstanding Entity Common Stock, Shares Outstanding Other comprehensive loss Other Comprehensive Income (Loss), Net of Tax Other Comprehensive Income (Loss), Net of Tax, Total Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table. Fair Value Assets Measured On Recurring Basis [Line Items] Fair Value Assets Measured On Recurring Basis [Line Items] Net income (loss) Net Income (Loss) Attributable to Parent Net income (loss) Operating lease liabilities Current portion of operating lease liabilities Current lease liability Roche license agreement. Roche License Agreement [Member] Roche License Agreement Additional Paid-in Capital [Member] Additional Paid-in Capital Document Information [Line Items] Entity Registrant Name Entity Registrant Name Cash and Cash Equivalents, at Carrying Value Cash and cash equivalents Cash and Cash Equivalents, at Carrying Value, Total Cash and Cash Equivalents, at Carrying Value, Beginning Balance Cash and Cash Equivalents, at Carrying Value, Ending Balance Earnings Per Share [Text Block] Net Income (Loss) Per Share Attributable to Common Stockholders U.S. Government agency securities US Government Agencies Debt Securities [Member] Lessee, Lease, Description [Table] Share-Based Payment Arrangement, Noncash Expense Stock-based compensation expense Share-based Payment Arrangement, Noncash Expense, Total Property, Plant and Equipment, Net Property and equipment, net Property, Plant and Equipment, Net, Total Property, Plant and Equipment, Net, Beginning Balance Property, Plant and Equipment, Net, Ending Balance Award Type [Domain] Statement [Line Items] Statement [Line Items] Title of 12(b) Security Title of 12(b) Security Increase (Decrease) in Accounts Payable Accounts payable Increase (Decrease) in Accounts Payable, Total Common Stock [Member] Common Stock Net Cash Provided by (Used in) Operating Activities [Abstract] Cash flows from operating activities Equity Component [Domain] Equity Component Fair Value Measurements Fair Value Measurement, Policy [Policy Text Block] Purchases of marketable securities Payments to Acquire Debt Securities, Available-for-Sale Revenue from Contract with Customer, Excluding Assessed Tax Collaboration revenue Revenue from Contract with Customer, Excluding Assessed Tax, Total Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest Income (loss) before income taxes The monetary allowance granted by the landlord to a tenant to entice tenant to move into landlords building which will enable the tenant to prepare the leased premises for tenants occupancy. Lease Hold Improvement Allowance Leasehold improvement allowance Entity Address, State or Province Entity Address, State or Province 2026 Lessee, Operating Lease, Liability, to be Paid, Year Four Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect Net decrease in cash, cash equivalents and restricted cash Document Type Document Type Jefferies LLC. Jefferies LLC [Member] Jeffries Entity Shell Company Entity Shell Company Share-Based Payment Arrangement, Expense Total stock-based compensation expense Corporate bonds Corporate Bond Securities [Member] Loss Contingencies [Line Items] Loss Contingencies [Line Items] Security Exchange Name Security Exchange Name Revenue from Contract with Customer [Abstract] Two thousand twenty incentive award plan. Two Thousand Twenty Incentive Award Plan [Member] 2020 Incentive Award Plan Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Less amount representing tenant improvement allowance Operating Lease Tenant Improvement Allowance Amount of lessee's undiscounted obligation for lease payments for operating lease for tenant improvement allowance. Net Cash Provided by (Used in) Operating Activities Net cash used in operating activities Commitments and Contingencies Disclosure [Abstract] Accrued Income Taxes, Current Income taxes Operating lease costs Operating Lease, Cost Restricted Stock Units Restricted Stock Units (RSUs) [Member] Lessee, Operating Lease, Liability, Maturity [Table Text Block] Summary of Future Minimum Payments under Operating Leases Consolidation, Policy [Policy Text Block] Principles of Consolidation New Accounting Pronouncements, Policy [Policy Text Block] Recently Adopted Accounting Pronouncements and Recently Issued Accounting Pronouncements Schedule of Defined Benefit Plans Disclosures [Table] Schedule Of Defined Benefit Plans Disclosures [Table] Principal office. Principal Office Member Principal Office Common Stock, Shares, Outstanding Common stock, shares outstanding Common Stock, Shares, Outstanding, Beginning Balance Common Stock, Shares, Outstanding, Ending Balance Fair Value, Inputs, Level 2 [Member] Level 2 Marketable Securities Available for Sale Fair Value Marketable securities Debt Securities, Available-for-Sale, Total Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities Commitments and contingencies (see Note 12) Commitments and Contingencies Common Stock, Shares, Issued Common stock, shares issued Common Stock, Shares, Issued, Total Number of shares issued Nature of business. Nature Of Business [Abstract] U.S. Treasury obligations US Treasury Securities [Member] Minimum Minimum [Member] Stockholders' Equity Attributable to Parent [Abstract] Stockholders’ equity: Income taxes payable Accrued Income Taxes, Noncurrent Counterparty Name [Axis] Counterparty Name Entity Address, Address Line Two Cash and Cash Equivalents [Axis] Cash and Cash Equivalents Award Type [Axis] Basis of Presentation and Significant Accounting Policies [Text Block] Summary of Significant Accounting Policies Loss Contingencies [Table] Loss Contingencies [Table] Lease expiration month and year Lease Expiration Month And Year Lease Expiration Month And Year Research and development expense Research and Development Expense Research and development Research and Development Expense, Total Lessee, Operating Lease, Liability, to be Paid Total lease payments Entity Central Index Key Entity Central Index Key The aggregate amount payable by the Company, as part of a consulting agreement. The payout amount is a success fee calculated as a percentage of certain product sales. Consulting Agreement Success Fee Payout Success fee Former Address Former Address [Member] Accounting Policies [Abstract] Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities Accrued expenses and other liabilities Debt Securities, Available-for-Sale [Line Items] Disaggregation of Revenue [Line Items] Disaggregation Of Revenue [Line Items] Number of shares available for future issuance Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant Common stock, capital shares reserved for future issuance Share-Based Payment Arrangement [Text Block] Stock-based Compensation General and Administrative Expense General and administrative General and Administrative Expense, Total Organization, Consolidation and Presentation of Financial Statements [Abstract] Document Information [Table] Research and Development Expense [Member] Research and Development Expense Open market sale agreement. Open Market Sale Agreement [Member] Sales Agreement Right of use assets obtained in exchange for operating lease liabilities Right-of-Use Asset Obtained in Exchange for Operating Lease Liability Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract] Adjustments to reconcile net income (loss) to net cash used in operating activities: Retained Earning/ (Accumulated Deficit) Retained Earnings [Member] Money Market Funds [Member] Money Market Funds From 2013 Plan From Two Thousand Thirteen Incentive Plan [Member] From Two Thousand Thirteen Incentive Plan [Member] Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Line Items] Two thousand and twenty employee stock purchase plan. Two Thousand and Twenty Employee Stock Purchase Plan [Member] 2020 Employee Stock Purchase Plan The aggregate credit recorded during the period to research and development expense as a result of adjustments to amounts originally reported and the close out of certain activities. Research and development credit adjustment Research and Development Credit Adjustment 2013 Incentive Plan Two Thousand Thirteen Incentive Plan [Member] Two thousand thirteen incentive plan. Percentage of commission of aggregate gross proceeds from each sale of shares. Percentage Of Commission Of Aggregate Gross Proceeds From Each Sale Of Shares Commission percentage of aggregate gross proceeds from each sale of shares Award vesting percentage Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage Additional Paid in Capital Additional paid-in capital Additional Paid in Capital, Total Additional Paid in Capital, Beginning Balance Additional Paid in Capital, Ending Balance Entity Interactive Data Current Entity Interactive Data Current Related Party Transactions Disclosure [Text Block] Related Party Transactions Entity controlled by director. Entity Controlled by Director [Member] Entity Controlled by Director Related Party Transactions [Abstract] 2023 Lessee, Operating Lease, Liability, to be Paid, Year One Local Phone Number Local Phone Number Fair Value, Assets Measured on Recurring Basis [Table Text Block] Schedule of Financial Assets Measured at Fair Value on Recurring Basis Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Summary of Basic and Diluted Earnings Per Share The entire disclosure for common stock, including, but not limited to, the number of shares issued and outstanding, voting rights, and number of shares reserved for each class of stock. Common Stock [Text Block] Common Stock Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items] Share Based Compensation Arrangement By Share Based Payment Award [Line Items] Basis of Accounting, Policy [Policy Text Block] Basis of Presentation Options granted Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross Income Statement Location [Domain] Income Statement Location Shares, Outstanding Balance, shares Balance, shares Increase (Decrease) in Prepaid Expense and Other Assets Prepaid expenses and other current assets Increase (Decrease) in Prepaid Expense and Other Assets, Total Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table] Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table] Location of additional office space. Location Of Additional Office Space Location of the additional office space Document Fiscal Year Focus Document Fiscal Year Focus 2024 Lessee, Operating Lease, Liability, to be Paid, Year Two Interest and Other Income Interest income and other, net Interest and Other Income, Total Earnings Per Share, Basic Basic Net income (loss) per share, basic Earnings Per Share, Basic, Total Compensation and Employee Benefit Plans [Text Block] Benefit Plan The commission rate the Company agreed to pay for shares sold under a Sales Agreement, as a percentage of aggregate gross sales proceeds from each sale of shares. Commission Rate Commission percentage of aggregate gross proceeds from each sale of shares Assets [Abstract] Assets Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents [Abstract] Cash, cash equivalents and restricted cash at the end of period: Prepaid Expense and Other Assets, Current Prepaid expenses and other current assets Amount of lessee's undiscounted obligation for lease payments for operating lease for tenant improvement allowance. Less amount representing future tenant improvement allowance Operating Lease Future Tenant Improvement Allowance Financial Instrument [Axis] Aggregate grant date fair market value The aggregate grant date fair value of options granted during the period. Share Based Compensation Arrangement By Share Based Payment Award Options Granted In Period Aggregate Grant Date Fair Value Long-Lived Tangible Asset [Axis] Liabilities and Equity [Abstract] Liabilities and Stockholders’ Equity Carrying value as of the balance sheet date of obligations incurred and payable for licensing arrangements. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). License fee Accrued License Fees Current Antidilutive Securities, Name [Domain] Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net income (loss) Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Assets, Current [Abstract] Current assets Securities maturing longer than one year Debt Securities, Available-for-Sale, Noncurrent Marketable debt securities, charges for credit-related impairments Debt Securities, Available-for-Sale, Allowance for Credit Loss, Not Previously Recorded Fair Value Hierarchy and NAV [Domain] Fair Value Hierarchy and NAV Payables and Accruals [Abstract] The aggregate amount of costs that have been, or will be, reimbursed by the licensee. Costs Reimbursed Amount Costs reimbursed amount Increase (Decrease) in Operating Capital [Abstract] Changes in operating assets and liabilities: Federal income taxes Federal Income Tax Expense (Benefit), Continuing Operations Federal Income Tax Expense (Benefit), Continuing Operations, Total Related Party Transaction [Line Items] Related Party Transaction [Line Items] Entity [Domain] Cover [Abstract] Product and Service [Domain] Product and Service Carrying value as of the balance sheet date of obligations incurred through that date and payable for professional fees, such as for legal and accounting services received, and fees classified as other. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer). Accrued Professional Fees And Other Current Professional fees and other Liabilities, Current [Abstract] Current liabilities Maximum [Member] Maximum Maximum Defined Contribution Plan, Employer Matching Contribution, Percent of Match Defined contribution plan, employer matching contribution, percentage Unrealized gains (losses) on available-for-sale investments OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block] Schedule of Stock-based Compensation Expense Net Cash Provided by (Used in) Investing Activities Net cash used in investing activities Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercises in Period Issuance of common stock upon exercise of stock options, shares Fair Value, Inputs, Level 3 [Member] Level 3 Summary of Stock-based Compensation Expense by Award Type Share-Based Payment Arrangement, Cost by Plan [Table Text Block] Use of Estimates, Policy [Policy Text Block] Use of Estimates Stock Issued During Period, Value, Stock Options Exercised Issuance of common stock upon exercise of stock options Defined Contribution Plan, Cost Defined contribution plan recognized expense related to matching contributions Common Stock, Shares Authorized Common stock, shares authorized Trading Symbol Trading Symbol Schedule of Marketable Securities Debt Securities, Available-for-Sale [Table Text Block] Title of Individual [Domain] Title of Individual Comprehensive income (loss) Comprehensive Income (Loss), Net of Tax, Attributable to Parent Accounts Payable, Current Accounts payable Accounts Payable, Current, Total Unrealized Losses Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax Increase (Decrease) in Other Operating Assets Other assets Increase (Decrease) in Other Operating Assets, Total Plan Name [Axis] Plan Name Schedule of Related Party Transactions, by Related Party [Table] Schedule Of Related Party Transactions By Related Party [Table] Title of Individual [Axis] Title of Individual Director [Member] Director Long-Lived Tangible Asset [Domain] Common Stock, Par or Stated Value Per Share Common stock, par value Lessor, Lease, Description [Line Items] Number of units granted Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period Defined Benefit Plan Disclosure [Line Items] Defined Benefit Plan Disclosure [Line Items] Number of additional shares authorized Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Additional Shares Authorized Increased number of shares available under incentive plan Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount Number of shares excluded from computation of diluted net income per share Indefinite-Lived Intangible Assets, Major Class Name [Domain] Indefinite-lived Intangible Assets, Major Class Name Cash equivalents Cash and Cash Equivalents, Fair Value Disclosure